6 questions you also want to know about probiotics

In the midst of the health and wellness craze, probiotics have emerged as a hot topic of discussion. From yogurt to probiotic supplements to various fermented foods, probiotics seem to be everywhere. However, amidst the plethora of products, we're left wondering: Are all probiotics the same? Are probiotic products with multiple strains the most effective? Do all fermented foods contain probiotics? Do all yogurts contain probiotics? Can probiotic products be used while taking antibiotics? And have probiotic strains undergone clinical research? Let's unravel these mysteries one by one.

1、Are all probiotics the same?

Answer: Definitely not! The power of probiotics resides in their unique strains, not just their genus or species. Just like siblings in a family, Lactobacillus and Bifidobacterium, two renowned probiotic genera, have individual strains with distinct personalities and purposes. Some Lactobacillus strains are the gentle, nurturing types, soothing diarrhea and healing gut wounds.

On the other hand, Bifidobacterium strains are the lively, energetic ones, promoting digestion and bowel movements while also regulating gut "moods," easing constipation, and keeping your digestive system in harmony.

When selecting probiotics, remember to focus on the strain, not just the genus or species. Find the one that speaks to your current gut health needs, and you'll unlock the full potential of probiotics for a healthier, happier you!
2、Are Probiotic Products with Multiple Strains the Most Successful?

Answer: Often, the answer leans towards a resounding "yes," but the story doesn't end there. Think of it like a symphony orchestra – each instrument (or strain, in this case) brings its unique melody to the performance, creating a harmonious whole that's greater than the sum of its parts. Multi-strain probiotic products have captured the spotlight in recent years, as they orchestrate a symphony of health benefits by blending complementary strains scientifically.

These products are like the ultimate gut health support team, tackling various aspects of digestive wellness from different angles. They create a thriving ecosystem within your gut, fostering an environment where probiotics can flourish and work together to crowd out harmful bacteria. It's a bit like having a well-trained army of good guys on your side, working in sync to keep the bad guys at bay.

But, here's the twist: just like not all orchestras are created equal, not all multi-strain probiotics deliver the same level of success. The secret sauce lies in the careful selection, precise blending, and scientific formulation of the right strains. It's not about quantity over quality; it's about finding the perfect ensemble that harmoniously addresses your unique gut health needs. So, while multi-strain probiotics often shine, it's essential to choose wisely and find the one that resonates best with your body's symphony.

3、Do All Fermented Foods Contain Probiotics?

Answer: Not quite, friend. Fermented foods are a diverse group, each with its own unique blend of microorganisms that contribute to their unique flavors and textures. However, not all of these microorganisms are probiotics.

For instance, soy sauce, vinegar, and rice wine undergo fermentation processes that involve various microorganisms, but they may not necessarily contain the specific strains of probiotics that are commonly associated with health benefits.

On the other hand, foods like yogurt, kimchi, and fermented tofu are often rich in probiotics. These friendly bacteria not only contribute to the overall flavor and nutritional value of these foods but also offer potential health benefits for the gut and overall well-being.

So, when selecting fermented foods, it's important to keep in mind that not all of them will be equally rich in probiotics. Choosing those that are known to contain beneficial probiotics can be a great way to incorporate these healthy bacteria into your diet.

4、Do All Yogurts Contain Probiotics?

Answer: Not quite every spoonful, but the majority do, if you know where to look. Yogurt comes in two main flavors of the probiotic world: the chilled and the shelf-steady.

The shelf-steady yogurts, like those that stand tall and proud on the pantry shelf, have been through a heat wave called pasteurization. This process is like a microbial exterminator, wiping out the live lactic acid bacteria that would otherwise bring probiotic joy to your gut. So, these yogurts are often probiotic-free zones.

But, step into the fridge aisle, and you'll find a different story. Regular, refrigerated yogurts are the probiotic party animals. They're made by inviting a variety of lactic acid bacteria to a milk-based dance party, where they ferment and multiply, leaving behind a tangy, creamy treat packed with active probiotics.

So, when you're in the mood for a probiotic boost from yogurt, make sure to grab a chilled variety from the fridge. Your gut will thank you for the dance!

5、Can Probiotic Products be Used While Taking Antibiotics?

Answer: The short answer is a friendly "yes, but with a twist of caution." You see, antibiotics are like a cleanup crew in your body, sweeping away harmful bacteria left and right. But sometimes, they can get a little overzealous and sweep up some of your gut's friendly probiotics too.

This little mishap can lead to a microbial mishmash in your gut, causing upset stomachs and diarrhea. That's where probiotics come in as the friendly reinforcements, helping to rebuild and restore the gut's microbial balance.

But, it's a delicate dance, friends. You don't want the probiotics and antibiotics to clash on the dance floor. So, timing is key. By taking them at different times of the day, you can ensure that both are doing their jobs without interfering with each other.

Always consult your healthcare provider before adding probiotics to your antibiotic routine. They'll be able to give you the specific recommendations that suit your unique situation, ensuring a smooth dance between health and happiness.

6、Have Probiotic Strains Undergone Clinical Research?

Answer: Oh, absolutely! Probiotic strains are like Olympic athletes before they hit the shelves. They go through a rigorous training regimen—I mean, clinical trials—to prove their worth.

It's a multi-step journey, starting with in vitro microbiological tests, where they show off their microbial prowess in a petri dish. Then, they move on to animal toxicity trials, where they prove they're not just strong but also safe to be around.

But, the real gold medal comes from human clinical trials. These studies put probiotics to the test, targeting specific health conditions to see if they can bring about positive changes. And, for those probiotics destined for baby bellies, the journey is even more intense, with multiple phases of research across different health areas to ensure they're safe and effective for little ones.

In conclusion, the world of probiotics is diverse and grounded in science. To fully harness their health benefits, approach probiotics with a mindful and informed attitude, selecting products wisely and using them appropriately.

Suitable probiotics for infants:

• Bifidobacterium: Improves intestinal microecological balance, promotes nutrient absorption, and plays a role in preventing constipation and diarrhea.
• Saccharomyces boulardii: Has a regulatory effect on intestinal issues such as diarrhea, can be used concurrently with antibiotics, and is not easily destroyed by antibiotics.
• Clostridium butyricum: Produces butyric acid, which provides energy for intestinal cells and contributes to intestinal health.
• Lactobacillus acidophilus: Helps regulate intestinal flora and enhances intestinal immunity.

• Lactobacillus Acidophilus: Enhances digestive health, supports vaginal health by maintaining a healthy pH balance, and helps prevent urinary tract infections.
• Bifidobacterium Lactis: Strengthens the immune system, aids in nutrient absorption, and promotes overall gut health, which in turn can positively impact women's overall wellbeing.
• Lactobacillus Plantarum: Promotes a healthy gut microbiome, aids in weight management, and has been linked to improved cardiovascular health, beneficial for women's long-term health.
• Lactobacillus Paracasei: Boosts immune function, enhances calcium absorption for bone health, and may also support skin health, addressing concerns that are of interest to many women.

Suitable probiotics for individuals with poor gut health

• Bifidobacterium: Strengthens gut immune function, enhances nutrient absorption, regulates gut pH, and inhibits the growth of harmful bacteria.
• Lactobacillus: Regulates gastrointestinal function, inhibits harmful bacteria, and maintains a balanced gut flora.
• Bacillus subtilis: Suppresses the proliferation of pathogenic bacteria, boosts gut resistance, and improves symptoms such as indigestion.
• Bacillus licheniformis: Exerts antagonistic effects against pathogenic bacteria, promotes the growth of beneficial bacteria, and adjusts gut flora imbalance.
• Saccharomyces boulardii: Provides a transient microecological adjustment, inhibits pathogenic microorganisms, and regulates gut flora.

Please note that while these probiotics offer positive effects on gut health, it's advisable to consult a doctor or nutritionist before use, especially for individuals with specific health concerns. Additionally, when selecting a probiotic product, ensure it is of good quality and contains sufficient live bacteria to ensure its effectiveness.

References:

• Goldenberg JZ, Yap C, Lytvyn L, et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database of Systematic Reviews. 2017;(12):CD006095. Accessed at www.cochranelibrary.com on January 23, 2018.
• Guarner F, Khan AG, Garisch J, et al. World Gastroenterology Organisation Global Guidelines. Probiotics and Prebiotics. October 2011. Journal of Clinical Gastroenterology. 2012;46(6):468–481.
• Rao SC, Athalye-Jape GK, Deshpande GC, et al. Probiotic supplementation and late-onset sepsis in preterm infants: a meta-analysis. Pediatrics. 2016;137(3):e20153684.
• Sanders ME, Akkermans LM, Haller D, et al. Safety assessment of probiotics for human use. Gut Microbes. 2010;1(3):164-185.
• U.S. Food and Drug Administration. Warning Regarding Use of Probiotics in Preterm Infants. Issued September 29, 2023. Accessed at https://www.fda.gov/media/172606 on October 2, 2023.
• Blaabjerg S, Artzi DM, Aabenhus R. Probiotics for the prevention of antibiotic-associated diarrhea in outpatients—a systematic review and meta-analysis. Antibiotics. 2017;6(4).pii:E21.
• Butel M-J. Probiotics, gut microbiota and health. Médecine et Maladies Infectieuses. 2014;44(1):1-8.